Ascorbyl palmitate
Ascorbyl palmitate is an ester formed from ascorbic acid and palmitic acid creating a fat-soluble form of vitamin C. In addition to its use as a source of vitamin C, it is also used as an antioxidant food additive (E number E304). It is approved for use as a food additive in the EU, the USA, Australia, and New Zealand.
Ascorbyl palmitate is known to be broken down (through the digestive process) into ascorbic acid and palmitic acid (a saturated fatty acid) before being absorbed into the bloodstream. Ascorbyl palmitate is also marketed as "vitamin C ester".
Ascorbic palmitate is esterified from palmitic acid and L-ascorbic acid and other natural ingredients. Its chemical formula is C22H38O7, which is a highly efficient oxygen scavger and synergist. It has been evaluated by the Food Additives Committee of the World Health Organization (WHO) as a nutritive, non-toxic, efficient and safe food additive. It is the only antioxidant that can be used in infant food in China. It can play the role of antioxidant, food (oil) color protection and nutrition enhancement when used in food.
Ascorbate palmitate is a kind of high efficiency, safe and non-toxic fat soluble nutritional antioxidant, which is difficult to dissolve in water and vegetable oil. White or yellowish-white powder with a slight citrus aroma.
L Ascorbic acid palmitic acid (referred to as VC ester) has efficient oxygen removal and nutritional strengthening functions, with all the physiological activities of vitamin C, while overcoming the three shortcomings of vitamin C, such as heat, light and tide. It has higher stability than vitamin C, and can provide vitamin C212g per 500g.
L-ascorbgyl palmitate (L-AP) is a new type of multi-functional food additive. Due to its unique function, L-AScorbgyl Palmitate has been widely used as fat-soluble antioxidant and nutritional enhancer in oil and food in China. Compared with L ascorbic acid, the antioxidant activity of L- ascorbic acid palmitate was significantly improved. Due to the implantation of palmitic acid group, it has both hydrophilic ascorbic acid group and oil-philic palmitic acid group, thus becoming an excellent surfactant 31. In addition, KageyamaK et al. also found that it can strongly inhibit THE DNA synthesis of Ehrlich ASCITES cancer cells and decompose the cell membrane phospholipids of cancer cells, which is an excellent anticancer substance. It can be predicted that L-ascorbic palmitate will be active in food, cosmetics and medical care products as a new and important multifunctional additive. [1]
In recent years, the application of L-AP has been expanded from the field of food, grain and oil to other fields. For example, it can be used as stabilizer in medicine ointment and capsule preparation, added in thermal paper to increase the stability of paper, added in cosmetics to enhance its efficacy, and has Antibacterial activity to bacillus subtilis and other. [2]
At present, L ascorbate palmitate production process mainly includes acyl chloride method, sulfuric acid method and lipase method. Acyl chloride method is highly corrosive: sulfuric acid method has a long reaction time and a large amount of waste acid generation, serious pollution: lipase method is not mature.
