Vitamin D2 is used to prevent vitamin D deficiency and treatment, such as: vegan, parenteral nutrition patients with pancreatic insufficiency malabsorption syndromes, liver and gallbladder disease (liver damage, cirrhosis, obstructive jaundice), intestinal disease (fatty diarrhea, Crohn's disease, chronic diarrhea), stomach resection.

Vitamin D2 is used for the treatment of chronic hypocalcemia, hypophosphatemia, rickets associated with chronic renal insufficiency and osteomalacia, familial hypophosphatemia and hypoparathyroidism (surgery, idiopathic or pseudo-hypoparathyroidism)

Vitamin D2 is used to treat acute and chronic and post-operative tetany potential disease and idiopathic tetany disease.