Promethazine hydrochloride

Promethazine hydrochloride is a kind of organic substance, chemical formula C17H20ClN2S, is a common cough medicine, is an antihistamine, can competitively block histamine H1 receptor, against histamine-induced telangiectasia, and reduce its permeability. Therefore, it can calm the cough caused by irritation of the trachea.

Pharmacological effects

It can block the H1 receptor of smooth muscle, capillary wall and other tissues, and thus play a competitive antagonistic effect with histamine. It can also have a significant central stability effect, and can strengthen the effect of anesthetics, hypnotics and analgesia. It can also lower body temperature and suppress vomiting.

Function of the attending

1, used for various allergies (such as asthma, urticaria, etc.), vomiting during pregnancy, dizziness caused by boat, etc.

2. It can be combined with aminophylline to treat asthma.

3. Mix with pethidine and other hibernation injection for artificial hibernation.

The editor of adverse reactions

(1) The main adverse reactions were drowsiness and dry mouth.

(2) Excessive use may cause dry mouth, nose and throat, abdominal pain, diarrhea, vomiting, lethargy and dizziness. Severe overdoses may result in convulsions, followed by central inhibition.

(3) Children with a large dose of this drug can produce delirium (symptoms of gibberish, mental excitement).

Matters needing attention

(1) Patients with pyloric obstruction, prostatic hypertrophy, bladder and neck obstruction, angleclosure glaucoma, hyperthyroidism and hypertension should be used with caution.

(2) Avoid driving vehicles, operating machines or working at heights during medication.

(3) People with renal dysfunction and a history of epilepsy should use with caution.

(4) It is not suitable for children under 3 months old.

(5) Acute poisoning can cause drowsiness, dizziness and dry mouth, nose, throat and abdominal pain, diarrhea, vomiting, etc. Severe poisoning may result in convulsions followed by central suppression. Right now usable stable static note, avoid uses central excitement medicine.

(6) Fanphenol thiazide drugs need to be noted, are applicable to this product.

(7) Photosensitized persons can no longer use it.