CAS 1950-1-1 Guanidine Hcl Solubility Msds Powder

Guanidine hydrochloride, chemically known as aminoformamidine hydrochloride, is a white or yellowish mass that is almost insoluble in acetone, benzene, and diethyl ether. Can be used as medicine, pesticides, dyes and their intermediates in organic synthesis, is manufacturing sulfadiazine, sulfanilamide methyl pyridine, sulfanilamide folic acid dimethyl pyrimidine and other drugs and important raw materials, also can be used as a synthetic fiber antistatic agent. White or yellowish clumps. Solubility of this product at 20℃ : 200g/100g water, 76g/100g methanol, 24g/100g ethanol. Almost insoluble in acetone, benzene and diethyl ether. USES used in organic synthesis and pharmaceutical industrial use mainly as the intermediate of medicines, is manufacturing sulfadiazine, sulfanilamide methyl pyridine, sulfanilamide dimethyl pyridine and folic acid USES available as the important raw materials in pharmaceutical, pesticide, dye and other organic synthesis intermediates.

Can be used to synthesize 2-aminopyrimidine, 2-aminopyrimidine, 2-aminopyrimidine, 2-aminopyrimidine, 6-dimethylopyrimidine, which is the intermediate of manufacturing sulfadiazine, sulfadimethylopyrimidine and other sulfa drugs. Guanidine hydrochloride (or guanidine nitrate) reacts with ethyl cyanoacetate, cyclization to 2, 4-diamino-6-hydroxy pyrimidine, used to synthesize the antianemia drug folic acid. Can also be used as synthetic fiber antistatic agent. Use as an intermediate in organic synthesis; Used as antistatic agent for synthetic fibers; Potent liquid dissociating agent for denaturation and subsequent renaturation of proteins.

This product is a broad spectrum Antibacterial agent, high concentration of bactericidal effect. This product of streptococcus pneumoniae, hemolytic streptococcus, grass green lotus aureus and part of staphylococcus aureus, and gas capsule coli, bacillus anthracis, y. pestis, corynebacterium diphtheriae, tetanus, undulant genera, h. influenzae, campylobacter, vibrio cholerae all has certain antibacterial activity, the rickettsia, mycoplasma, chlamydia, helix, some parasite has inhibitory effect. Enterobacteriaceae bacteria such as Escherichia coli, Klebsiella, Salmonella, Shigella and so on are mostly resistant to this product.

The effect of this product on Gram-positive bacteria is better than that of Gram-positive bacteria, but Enterococcus is resistant to it. Others such as Actinomycetes, Bacillus anthracis, Listeria monocytogenes, Clostridium SPP., Nocardia SPP., etc., are also sensitive to this product. This product is also resistant to tetracycline for gonococci. This product has certain antibacterial activity against Neisseria gonorrhoeae and Neisseria meningitidis, but penicillin-resistant Neisseria gonorrhoeae is also resistant to tetracycline. The mechanism of action of this product is that the drug can specifically bind to the A position of the 30S subunit of the bacterial ribosome, where the binding of anaminoacyl-trNA can inhibit the growth of peptide chain and affect the synthesis of bacterial protein.