Unit Price: | 3.5~4 USD |
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Payment Type: | L/C,T/T,D/P,D/A,Others |
Incoterm: | FOB,CFR,CIF,EXW,FCA,CPT,CIP |
Min. Order: | 1 Gram |
Model No.: HRK-Ibrutinib
Brand: Henrikang
Appearance: White Powder
Storage: Cool Dry Place
Shelf Life: 2 Years
Specification: 99%min
Test Method: Hplc
Certificate: Iso9001
CAS: 936563-96-1
Product Name: Hrk-Ibrutinib
MF: C25h24n6o2
Keywords: Ibrutinib Anticoagulation
Packaging: 1kg per bag. or customized packaging.
Productivity: 100000kg
Transportation: Ocean,Land,Air,Express
Place of Origin: Shaanxi,China
Supply Ability: 600000kg/months
Certificate: ISO
HS Code: N/A
Port: Guangzhou,Qingdao,Shanghai
Payment Type: L/C,T/T,D/P,D/A,Others
Incoterm: FOB,CFR,CIF,EXW,FCA,CPT,CIP
Buy online CAS936563-96-1 ibrutinib and venetoclax powder
Product Name:Buy online CAS936563-96-1 ibrutinib and venetoclax powder
CAS:936563-96-1
MF:C25H24N6O2
Test Method:HPLC
Storage: 2 Years
Shelf Life : Cool Dry Place
What is ibrutinib powder?
Ibrutinib is a highly selective Bruton's tyrosine kinase (Btk) irreversible inhibitor.PCI-32765 (Ibrutinib) is a selective and irreversible pyrrolopyrimidine-based inhibitor of BTK with IC50 of 0.5 nM. [1] PCI-32765 binds irreversibly to Cys-481 in BTK and thus is only active with other kinases with such a modifiable cysteine residue. In DOHH2 cells, in which the BCR pathway can be activated by anti-IgG, PCI-32765 inhibits autophosphorylation of BTK (IC50, 11 nM), BTK's physiological substrate, PLCg (IC50, 29 nm), and downstream ERK (IC50, 13 nm).
Function&Application of ibrutinib powder
Ibrutinib is a high potent irreversible BTK inhibitor with an IC50 of 0.46 nM for the purified Btk.PCI-32765 (Ibrutinib) is highly active and well tolerated in CLL/SLL pts irrespective of high risk genomic abnormalities. Although follow-up is short, the high response rate and very low progression rate suggests that PCI-32765 (Ibrutinib) may be an important new targeted treatment approach for CLL pts. In ex vivo assays with whole bold, PCI-32765 (Ibrutinib) prevents the activation of human BCR with an IC50 of about 0.2 μM, while not influencing the activation of T cell.
Product Name | Buy online CAS936563-96-1 ibrutinib and venetoclax powder |
Appearance | White Powder |
Test | HPLC |
Certificate | ISO 9001 |
specification | 99% min |
Keywords | ibrutinib powder supply, ibrutinib powder manufacturer |
Product Categories : Human APIs > Kidney Medicine powder