Factory Price CAS 67-20-9 Nitrofurantoin And Alcohol Powder

The mechanism of action of nitrofurantoin is unique and complex. The drug works by damaging bacterial DNA, since its reduced form is highly reactive.This is made possible by the rapid reduction of nitrofurantoin inside the bacterial cell by flavoproteins(nitrofuran reductase) to multiple reactive intermediates that attack ribosomal proteins, DNA,respiration, pyruvate metabolism and other macromolecules within the cell. Nitrofurantoin exerts greater effects on bacterial cells than mammalian cells because bacterial cells activate the drug more rapidly. It is not known which of the actions of nitrofurantoin is primarily responsible for its bactericidal activity. The broad mechanism of action for this drug likely is responsible for the low development of resistance to its effects, as the drug affects many different processes important to the bacterial ce

Organic synthesis and Biochemical research. Medicine. This product is a kind of excellent Antibacterial drug, antibacterial spectrum is wide, after oral absorption quickly and completely, excretion is also fast, the amount of excretion in urine can reach 40-50%, often used for the treatment of various sensitive bacteria caused by urinary tract infection. It has effect on gram negative and positive bacteria, mainly used for urinary tract infection caused by sensitive bacteria, especially for acute urinary tract infection caused by Escherichia coli and Proteus. Clinical use for sensitive bacteria caused by urinary system infection, such as pyelonephritis, urinary tract infection, cystitis and prostatitis.

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